Every now and then an article comes around that just fascinates me. A perfect example is the following paper from 2014…

Leukotriene B4 amplifies eosinophil accumulation in response to nematodes.

I know what you’re thinking…

awesome(Okay, maybe not…)

The study is actually pretty straightforward. It focuses on how a certain molecule, leukotriene B4, which is produced by a particular type of immune cell, an eosinophil, prompts other eosinophils to migrate to a particular enemy, in this case a parasitic worm. Simple, right?

sayagain(Okay, maybe not…)

The problem with a scientific article such as this one is the rather complex nature of the work and the mechanism the researchers discovered. Trying to explain this process could be an exercise in frustration. One needs to understand the cascade effect of immunity, the arachidonic acid biochemical pathway, and the biology of worms. Getting to the point could take as many or perhaps more words than the original article.

But there may be a better way to describe what is happening….

attack(You have to feel a little sorry for the worm…)

What you are seeing in this GIF is a time lapse video of eosinophils migrating towards a worm. Even more incredible is the length of time this video covers…only 80 minutes. In the context of the usually slow process by which biological life exists, this is what we call as fast as…

bolt(You get the idea…)

But while the rapid effect of a leukotriene on eosinophil migration in the battle against a worm may be just the bees knees for me, I can understand why this may not make you sit back in awe.

Of course, that is until I tell you there is a reason why you may find this information of interest. The same process witnessed above also happens when some people suffer…

asthma(Asthma or allergies or other respiratory distress…)

Even though the paper may not be worth the entire read, the GIF may be able to provide perspective on a significant health problem.

What I hope this also does is highlight the importance of fundamental research. While these types of studies may not seem to have any link to human health, when you widen the scope to what plagues us, then you may end up saying…

relevant(Even if the paper is upside down…)

After all, not all science is glamorous, but that doesn’t make it any less valuable.

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